PGF Antibody

ProSci
Product Code: PSI-57-830
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-830-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).
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PGF Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in CEM cell line lysates (35ug/lane).
PGF Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Placenta growth factor, PlGF, PGF, PGFL, PLGF
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The PGF gene encodes placenta growth factor, a homolog of vascular endothelial growth factor (VEGFA; MIM 192240), that selectively binds to VEGFR1 (FLT1; MIM 165070) and is involved in angiogenesis (Fischer et al., 2007 [PubMed 17981115]; Bais et al., 2010 [PubMed 20371352]).
Background References:
  • Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
  • Cowans, N.J., et al. Prenat. Diagn. 30(6):565-570(2010)
  • Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
  • Andersson, M.K., et al. BMC Cancer 10, 249 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human PGF.
NCBI Gene ID #:
5228
NCBI Official Name:
Placenta growth factor
NCBI Official Symbol:
PGF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P49763
Protein GI Number:
17380553
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P49763
User NOte:
Optimal dilutions for each application to be determined by the researcher.