FUT8 Antibody
| Code | Size | Price |
|---|
| PSI-55-648-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-(1,6)-fucosyltransferase, Alpha1-6FucT, Fucosyltransferase 8, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase, GDP-fucose--glycoprotein fucosyltransferase, Glycoprotein 6-alpha-L-fucosyltransferase, FUT8
Application Note:
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
For WB starting dilution is: 1:1000
Background:
This enzyme belongs to the family of fucosyltransferases.
The product of this gene catalyzes the transfer of fucose from
GDP-fucose to N-linked type complex glycopeptides. This enzyme is
distinct from other fucosyltransferases which catalyze alpha1-2,
alpha1-3, and alpha1-4 fucose addition. The expression of this gene
may contribute to the malignancy of cancer cells and to their
invasive and metastatic capabilities. Alternatively spliced
variants encoding different isoforms have been identified.
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Wang, X., et al. J. Biochem. 145(5):643-651(2009)
- Kudo, T., et al. Mol. Cancer 6, 32 (2007) :
- Ihara, H., et al. Glycobiology 16(4):333-342(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig, Bovine
Immunogen:
This FUT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human FUT8.
NCBI Gene ID #:
2530
NCBI Official Name:
Alpha-(1,6)-fucosyltransferase
NCBI Official Symbol:
FUT8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
Q9BYC5
Protein GI Number:
20138326
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q9BYC5
User NOte:
Optimal dilutions for each application to be determined by the researcher.