SCP2 Antibody
| Code | Size | Price |
|---|
| PSI-56-475-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Non-specific lipid-transfer protein, NSL-TP, Propanoyl-CoA C-acyltransferase, SCP-chi, SCPX, Sterol carrier protein 2, SCP-2, Sterol carrier protein X, SCP-X, SCP2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes two proteins: sterol carrier protein X
(SCPx) and sterol carrier protein 2 (SCP2), as a result of
transcription initiation from 2 independently regulated promoters.
The transcript initiated from the proximal promoter encodes the
longer SCPx protein, and the transcript initiated from the distal
promoter encodes the shorter SCP2 protein, with the 2 proteins
sharing a common C-terminus. Evidence suggests that the SCPx
protein is a peroxisome-associated thiolase that is involved in the
oxidation of branched chain fatty acids, while the SCP2 protein is
thought to be an intracellular lipid transfer protein. This gene is
highly expressed in organs involved in lipid metabolism, and may
play a role in Zellweger syndrome, in which cells are deficient in
peroxisomes and have impaired bile acid synthesis. Alternative
splicing of this gene produces multiple transcript variants, some
encoding different isoforms.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Rikova, K., et al. Cell 131(6):1190-1203(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human SCP2.
NCBI Gene ID #:
6342
NCBI Official Name:
Non-specific lipid-transfer protein
NCBI Official Symbol:
SCP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
P22307
Protein GI Number:
2507456
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P22307
User NOte:
Optimal dilutions for each application to be determined by the researcher.