ABCC3 Antibody
| Code | Size | Price |
|---|
| PSI-55-057-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, Multi-specific organic anion transporter D, MOAT-D, Multidrug resistance-associated protein 3, ABCC3, CMOAT2, MLP2, MRP3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the
superfamily of ATP-binding cassette (ABC) transporters. ABC
proteins transport various molecules across extra- and
intra-cellular membranes. ABC genes are divided into seven distinct
subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This
protein is a member of the MRP subfamily which is involved in
multi-drug resistance. The specific function of this protein has
not yet been determined; however, this protein may play a role in
the transport of biliary and intestinal excretion of organic
anions. Alternatively spliced variants which encode different
protein isoforms have been described; however, not all variants
have been fully characterized.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Hoffman, A.D., et al. Protein J. 29(5):373-379(2010)
- Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ABCC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 899-925 amino acids from the Central region of human ABCC3.
NCBI Gene ID #:
8714
NCBI Official Name:
Canalicular multispecific organic anion transporter 2
NCBI Official Symbol:
ABCC3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
169 kDa
Protein Accession #:
O15438
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
O15438
User NOte:
Optimal dilutions for each application to be determined by the researcher.