ABCC10 Antibody

ProSci
Product Code: PSI-55-056
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-056-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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ABCC10 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
ABCC10 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Multidrug resistance-associated protein 7, ATP-binding cassette sub-family C member 10, ABCC10, MRP7, SIMRP7
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Kuang, Y.H., et al. Biochem. Pharmacol. 79(2):154-161(2010)
  • Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
  • Zhou, Y., et al. Biochem. Pharmacol. 77(6):993-1001(2009)
  • Hopper-Borge, E., et al. Cancer Res. 69(1):178-184(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 amino acids from the Central region of human ABCC10.
NCBI Gene ID #:
89845
NCBI Official Name:
Multidrug resistance-associated protein 7
NCBI Official Symbol:
ABCC10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
162 kDa
Protein Accession #:
Q5T3U5
Protein GI Number:
74756298
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q5T3U5
User NOte:
Optimal dilutions for each application to be determined by the researcher.