EDN1 Antibody
| Code | Size | Price |
|---|
| PSI-56-152-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1
Application Note:
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
Background:
The protein encoded by this gene is proteolytically
processed to release a secreted peptide termed endothelin 1. This
peptide is a potent vasoconstrictor and is produced by vascular
endothelial cells. Endothelin 1 also can affect the central nervous
system. Two transcript variants encoding different isoforms have
been found for this gene.
Background References:
- Gonsalves, C., et al. J. Immunol. 185(10):6253-6264(2010)
- Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
- Feng, J., et al. Circulation 122 (11 SUPPL), S150-S155 (2010) :
- Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(9):748-756(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the C-terminal region of human EDN1.
NCBI Gene ID #:
1906
NCBI Official Name:
Endothelin-1
NCBI Official Symbol:
EDN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
P05305
Protein GI Number:
119610
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P05305
User NOte:
Optimal dilutions for each application to be determined by the researcher.