LDHA Antibody
| Code | Size | Price |
|---|
| PSI-57-107-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
L-lactate dehydrogenase A chain, LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, LDHA
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene catalyzes the conversion
of L-lactate and NAD to pyruvate and NADH in the final step of
anaerobic glycolysis. The protein is found predominantly in muscle
tissue and belongs to the lactate dehydrogenase family. Mutations
in this gene have been linked to exertional myoglobinuria. Multiple
transcript variants encoding different isoforms have been found for
this gene. The human genome contains several non-transcribed
pseudogenes of this gene.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Zhu, X., et al. Genet. Epidemiol. 34(2):171-187(2010)
- Zhuang, L., et al. Mod. Pathol. 23(1):45-53(2010)
- Zhao, Y.H., et al. Oncogene 28(42):3689-3701(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This LDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the C-terminal region of human LDHA.
NCBI Gene ID #:
3939
NCBI Official Name:
L-lactate dehydrogenase A chain
NCBI Official Symbol:
LDHA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
P00338
Protein GI Number:
126047
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P00338
User NOte:
Optimal dilutions for each application to be determined by the researcher.