AMOT Antibody
| Code | Size | Price |
|---|
| PSI-60-019-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Angiomotin, AMOT, KIAA1071
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the motin family of angiostatin
binding proteins characterized by conserved coiled-coil domains and
C-terminal PDZ binding motifs. The encoded protein is expressed
predominantly in endothelial cells of capillaries as well as larger
vessels of the placenta where it may mediate the inhibitory effect
of angiostatin on tube formation and the migration of endothelial
cells toward growth factors during the formation of new blood
vessels. Alternative splicing results in multiple transcript
variants encoding different isoforms.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Heller, B., et al. J. Biol. Chem. 285(16):12308-12320(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Gagne, V., et al. Cell Motil. Cytoskeleton 66(9):754-768(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AMOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-267 amino acids from the N-terminal region of human AMOT.
NCBI Gene ID #:
154796
NCBI Official Name:
Angiomotin
NCBI Official Symbol:
AMOT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
118 kDa
Protein Accession #:
Q4VCS5
Protein GI Number:
74753814
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q4VCS5
User NOte:
Optimal dilutions for each application to be determined by the researcher.