HBEGF Antibody
| Code | Size | Price |
|---|
| PSI-58-020-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Proheparin-binding EGF-like growth factor, Heparin-binding EGF-like growth factor, HB-EGF, HBEGF, Diphtheria toxin receptor, DT-R, HBEGF, DTR, DTS, HEGFL
Application Note:
For WB starting dilution is: 1:1000
Background:
HBEGF may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rahman, F.B., et al. Lab. Invest. 90(7):1033-1048(2010)
- Hamaoka, M., et al. J. Biochem. 148(1):55-69(2010)
- Smirnova, I.S., et al. Tsitologiia 52(5):357-363(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HBEGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the Central region of human HBEGF.
NCBI Gene ID #:
1839
NCBI Official Name:
Proheparin-binding EGF-like growth factor
NCBI Official Symbol:
HBEGF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
Q99075
Protein GI Number:
544477
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q99075
User NOte:
Optimal dilutions for each application to be determined by the researcher.