PPP1R13B Antibody
| Code | Size | Price |
|---|
| PSI-59-018-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B, PPP1R13B, ASPP1, KIAA0771
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the ASPP
(apoptosis-stimulating protein of p53) family of p53 interacting
proteins. The protein contains four ankyrin repeats and an SH3
domain involved in protein-protein interactions. ASPP proteins are
required for the induction of apoptosis by p53-family proteins.
They promote DNA binding and transactivation of p53-family proteins
on the promoters of proapoptotic genes. Expression of this gene is
regulated by the E2F transcription factor.
Background References:
- Figl, A., et al. Mutat. Res. 702(1):8-16(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Zhao, J., et al. Hepatology 51(1):142-153(2010)
- Agirre, X., et al. Oncogene 25(13):1862-1870(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PPP1R13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-652 amino acids from the Central region of human PPP1R13B.
NCBI Gene ID #:
23368
NCBI Official Name:
Apoptosis-stimulating of p53 protein 1
NCBI Official Symbol:
PPP1R13B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
120 kDa
Protein Accession #:
Q96KQ4
Protein GI Number:
296439434
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q96KQ4
User NOte:
Optimal dilutions for each application to be determined by the researcher.