NUP88 Antibody
| Code | Size | Price |
|---|
| PSI-57-528-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nuclear pore complex protein Nup88, 88 kDa nucleoporin, Nucleoporin Nup88, NUP88
Application Note:
For WB starting dilution is: 1:1000
Background:
The nuclear pore complex is a massive structure that
extends across the nuclear envelope, forming a gateway that
regulates the flow of macromolecules between the nucleus and the
cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the
main components of the nuclear pore complex in eukaryotic cells.
The protein encoded by this gene belongs to the nucleoporin family
and is associated with the oncogenic nucleoporin CAN/Nup214 in a
dynamic subcomplex. This protein is also overexpressed in a large
number of malignant neoplasms and precancerous dysplasias.
Background References:
- Hashizume, C., et al. Mol. Cancer 9, 119 (2010) :
- Brustmann, H., et al. Ann Diagn Pathol 13(5):303-307(2009)
- Cheng, Y.T., et al. Plant Cell 21(8):2503-2516(2009)
- Andres-Hernando, A., et al. J. Biol. Chem. 283(36):25082-25090(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This NUP88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-730 amino acids from the C-terminal region of human NUP88.
NCBI Gene ID #:
4927
NCBI Official Name:
Nuclear pore complex protein Nup88
NCBI Official Symbol:
NUP88
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
Q99567
Protein GI Number:
25008854
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q99567
User NOte:
Optimal dilutions for each application to be determined by the researcher.