IQGAP1 Antibody
| Code | Size | Price |
|---|
| PSI-58-784-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ras GTPase-activating-like protein IQGAP1, p195, IQGAP1, KIAA0051
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the IQGAP family. The
protein contains four IQ domains, one calponin homology domain, one
Ras-GAP domain and one WW domain. It interacts with components of
the cytoskeleton, with cell adhesion molecules, and with several
signaling molecules to regulate cell morphology and motility.
Expression of the protein is upregulated by gene amplification in
two gastric cancer cell lines.
Background References:
- Hayashi, H., et al. Int. J. Cancer 126(11):2563-2574(2010)
- Liang, S., et al. Proteomics 10(7):1474-1483(2010)
- Nakhaei-Nejad, M., et al. Eur. J. Immunol. 40(1):204-213(2010)
- Wang, J.B., et al. J. Cell. Sci. 122 (PT 12), 2024-2033 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This IQGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the N-terminal region of human IQGAP1.
NCBI Gene ID #:
8826
NCBI Official Name:
Ras GTPase-activating-like protein IQGAP1
NCBI Official Symbol:
IQGAP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
189 kDa
Protein Accession #:
P46940
Protein GI Number:
1170586
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P46940
User NOte:
Optimal dilutions for each application to be determined by the researcher.