CDCP1 Antibody
| Code | Size | Price |
|---|
| PSI-58-436-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
CUB domain-containing protein 1, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, CD318, CDCP1, TRASK
Application Note:
For WB starting dilution is: 1:1000
Background:
CDCP1 is a transmembrane
protein containing three extracellular CUB domains. This protein is
found to be overexpressed in colon and lung cancers. Its expression
level is correlated with the metastatic ability of carcinoma cells.
This protein is located on the cell surface. It has been shown to
be tyrosine phosphorylated in a cancer cell line. Alternatively
spliced transcript variants encoding distinct isoforms have been
reported.
Background References:
- He, Y., et al. J. Biol. Chem. 285(34):26162-26173(2010)
- Miyazawa, Y., et al. Cancer Res. 70(12):5136-5146(2010)
- Mamat, S., et al. Oncol. Rep. 23(5):1221-1227(2010)
- Fukuchi, K., et al. Mol. Pharm. 7(1):245-253(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 704-732 amino acids from the C-terminal region of human CDCP1.
NCBI Gene ID #:
64866
NCBI Official Name:
CUB domain-containing protein 1
NCBI Official Symbol:
CDCP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
93 kDa
Protein Accession #:
Q9H5V8
Protein GI Number:
317373455
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q9H5V8
User NOte:
Optimal dilutions for each application to be determined by the researcher.