RAB8B Antibody

ProSci
Product Code: PSI-60-277
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-277-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).

Western blot analysis in Jurkat cell line lysates (35ug/lane).

Further Information

Additional Names:
Ras-related protein Rab-8B, RAB8B
Application Note:
For WB starting dilution is: 1:1000
Background:
RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).
Background References:
  • Heidrych, P., et al. Hum. Mol. Genet. 17(23):3814-3821(2008)
  • Wu, C., et al. Proteomics 7(11):1775-1785(2007)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Lau, A.S., et al. Endocrinology 144(4):1549-1563(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This RAB8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-198 amino acids from the C-terminal region of human RAB8B.
NCBI Gene ID #:
51762
NCBI Official Name:
Ras-related protein Rab-8B
NCBI Official Symbol:
RAB8B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
Q92930
Protein GI Number:
13638434
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q92930
User NOte:
Optimal dilutions for each application to be determined by the researcher.