ARHGAP24 Antibody

ProSci
Product Code: PSI-57-297
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-297-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

Further Information

Additional Names:
Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, ARHGAP24, FILGAP
Application Note:
For WB starting dilution is: 1:1000
Background:
ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).
Background References:
  • Horinouchi, M., et al. Pediatr Hematol Oncol 27(5):344-354(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Holm, H., et al. Nat. Genet. 42(2):117-122(2010)
  • Pfeufer, A., et al. Nat. Genet. 42(2):153-159(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ARHGAP24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 587-616 amino acids from the C-terminal region of human ARHGAP24.
NCBI Gene ID #:
83478
NCBI Official Name:
Rho GTPase-activating protein 24
NCBI Official Symbol:
ARHGAP24
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
Q8N264
Protein GI Number:
134035016
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q8N264
User NOte:
Optimal dilutions for each application to be determined by the researcher.