CACNB1 Antibody
| Code | Size | Price |
|---|
| PSI-58-291-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Voltage-dependent L-type calcium channel subunit beta-1, CAB1, Calcium channel voltage-dependent subunit beta 1, CACNB1, CACNLB1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the calcium
channel beta subunit family. It plays an important role in the
calcium channel by modulating G protein inhibition, increasing peak
calcium current, controlling the alpha-1 subunit membrane targeting
and shifting the voltage dependence of activation and inactivation.
Alternative splicing occurs at this locus and three transcript
variants encoding three distinct isoforms have been identified.
Background References:
- Jangsangthong, W., et al. Pflugers Arch. 459(3):399-411(2010)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Lim, J., et al. Cell 125(4):801-814(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This CACNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-572 amino acids from the C-terminal region of human CACNB1.
NCBI Gene ID #:
782
NCBI Official Name:
Voltage-dependent L-type calcium channel subunit beta-1
NCBI Official Symbol:
CACNB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
Q02641
Protein GI Number:
20455481
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q02641
User NOte:
Optimal dilutions for each application to be determined by the researcher.