MAFA Antibody

ProSci
Product Code: PSI-63-946
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-946-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of MAFA Antibody in WiDr cell line lysates (35ug/lane)

Western blot analysis of MAFA Antibody in WiDr cell line lysates (35ug/lane)

Further Information

Additional Names:
Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Application Note:
For WB starting dilution is: 1:1000
Background:
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene.
Background References:
  • Kondo, T., et al. Mol. Endocrinol. 23(8):1281-1290(2009)
  • Kaneto, H., et al. Adv. Drug Deliv. Rev. 61 (7-8), 489-496 (2009)
  • Garin, I., et al. Diabet. Med. 26(7):746-748(2009)
  • Vanderford, N.L., et al. Arch. Biochem. Biophys. 480(2):138-142(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This MAFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-311 amino acids from the C-terminal region of human MAFA.
NCBI Gene ID #:
389692
NCBI Official Name:
Transcription factor MafA
NCBI Official Symbol:
MAFA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q8NHW3
Protein GI Number:
296435511
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q8NHW3
User NOte:
Optimal dilutions for each application to be determined by the researcher.