MAFA Antibody
| Code | Size | Price |
|---|
| PSI-58-295-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Application Note:
For WB starting dilution is: 1:1000
Background:
MAFA is a transcription factor that binds RIPE3b, a
conserved enhancer element that regulates pancreatic beta
cell-specific expression of the insulin gene (INS; MIM 176730)
(Olbrot et al., 2002 [PubMed 12011435]).
Background References:
- Lecoin, L., et al. Dev Neurobiol 70(7):485-497(2010)
- Guo, S., et al. J. Biol. Chem. 285(17):12655-12661(2010)
- Kondo, T., et al. Mol. Endocrinol. 23(8):1281-1290(2009)
- Kaneto, H., et al. Adv. Drug Deliv. Rev. 61 (7-8), 489-496 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This MAFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of human MAFA.
NCBI Gene ID #:
389692
NCBI Official Name:
Transcription factor MafA
NCBI Official Symbol:
MAFA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q8NHW3
Protein GI Number:
296435511
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q8NHW3
User NOte:
Optimal dilutions for each application to be determined by the researcher.