ITGA7 Antibody
| Code | Size | Price |
|---|
| PSI-60-160-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Integrin alpha-7, Integrin alpha-7 heavy chain, Integrin alpha-7 light chain, Integrin alpha-7 70 kDa form, ITGA7
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the integrin
alpha chain family. Integrins are heterodimeric integral membrane
proteins composed of an alpha chain and a beta chain. They mediate
a wide spectrum of cell-cell and cell-matrix interactions, and thus
play a role in cell migration, morphologic development,
differentiation, and metastasis. This protein functions as a
receptor for the basement membrane protein laminin-1. It is mainly
expressed in skeletal and cardiac muscles and may be involved in
differentiation and migration processes during myogenesis. Defects
in this gene are associated with congenital myopathy. Alternatively
spliced transcript variants encoding different isoforms have been
noted for this gene.
Background References:
- Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
- Han, Y.C., et al. Cancer Res. 70(11):4375-4384(2010)
- Rooney, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(19):7991-7996(2009)
- Liu, J., et al. J. Biol. Chem. 283(51):35668-35678(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ITGA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the N-terminal region of human ITGA7.
NCBI Gene ID #:
3679
NCBI Official Name:
Integrin alpha-7
NCBI Official Symbol:
ITGA7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
129 kDa
Protein Accession #:
Q13683
Protein GI Number:
308153592
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q13683
User NOte:
Optimal dilutions for each application to be determined by the researcher.