GNAS Antibody
Code | Size | Price |
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PSI-62-509-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, Adenylate cyclase-stimulating G alpha protein, Extra large alphas protein, XLalphas, GNAS, GNAS1 {ECO:0000303|PubMed:9707596}
Application Note:
For WB starting dilution is: 1:4000
Background:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
Background References:
- Liu,C., et.al., Eur Arch Otorhinolaryngol (2009)
- Nishihara,E., et.al., Endocr. J. 56 (6), 791-798 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-667 amino acids from the Central region of human GNAS.
NCBI Gene ID #:
2778
NCBI Official Name:
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
NCBI Official Symbol:
GNAS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
111 kDa
Protein Accession #:
Q5JWF2
Protein GI Number:
116248089
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q5JWF2
User NOte:
Optimal dilutions for each application to be determined by the researcher.