GNAS Antibody

ProSci
Product Code: PSI-62-509
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-509-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:4000 dilution + Ramos whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:4000 dilution + Ramos whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, Adenylate cyclase-stimulating G alpha protein, Extra large alphas protein, XLalphas, GNAS, GNAS1 {ECO:0000303|PubMed:9707596}
Application Note:
For WB starting dilution is: 1:4000
Background:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
Background References:
  • Liu,C., et.al., Eur Arch Otorhinolaryngol (2009)
  • Nishihara,E., et.al., Endocr. J. 56 (6), 791-798 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-667 amino acids from the Central region of human GNAS.
NCBI Gene ID #:
2778
NCBI Official Name:
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
NCBI Official Symbol:
GNAS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
111 kDa
Protein Accession #:
Q5JWF2
Protein GI Number:
116248089
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q5JWF2
User NOte:
Optimal dilutions for each application to be determined by the researcher.