GRAP2 Antibody
| Code | Size | Price |
|---|
| PSI-57-955-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
GRB2-related adapter protein 2, Adapter protein GRID, GRB-2-like protein, GRB2L, GRBLG, GRBX, Grf40 adapter protein, Grf-40, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, P38, Protein GADS, SH3-SH2-SH3 adapter Mona, GRAP2, GADS, GRB2L, GRID
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the GRB2/Sem5/Drk family.
This member is an adaptor-like protein involved in
leukocyte-specific protein-tyrosine kinase signaling. Like its
related family member, GRB2-related adaptor protein (GRAP), this
protein contains an SH2 domain flanked by two SH3 domains. This
protein interacts with other proteins, such as GRB2-associated
binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2),
through its SH3 domains. Transcript variants utilizing alternative
polyA sites exist.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Preisinger, C., et al. Cell. Signal. 22(5):848-856(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GRAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 amino acids from the Central region of human GRAP2.
NCBI Gene ID #:
9402
NCBI Official Name:
GRB2-related adapter protein 2
NCBI Official Symbol:
GRAP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
O75791
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
O75791
User NOte:
Optimal dilutions for each application to be determined by the researcher.