SCGB1D2 Antibody
Code | Size | Price |
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PSI-57-276-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Secretoglobin family 1D member 2, Lipophilin-B, SCGB1D2, LIPHB, LPNB
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
lipophilin subfamily, part of the uteroglobin superfamily, and is
an ortholog of prostatein, the major secretory glycoprotein of the
rat ventral prostate gland. Lipophilin gene products are widely
expressed in normal tissues, especially in endocrine-responsive
organs. Assuming that human lipophilins are the functional
counterparts of prostatein, they may be transcriptionally regulated
by steroid hormones, with the ability to bind androgens, other
steroids and possibly bind and concentrate estramustine, a
chemotherapeutic agent widely used for prostate cancer. Although
the gene has been reported to be on chromosome 10, this sequence
appears to be from a cluster of genes on chromosome 11 that
includes mammaglobin 2.
Background References:
- Sjodin, A., et al. Anticancer Res. 28 (3A), 1493-1498 (2008) :
- Culleton, J., et al. Int. J. Cancer 120(5):1087-1092(2007)
- Sjodin, A., et al. Acta Neuropathol. 109(4):381-386(2005)
- Carter, D., et al. Clin. Cancer Res. 9(2):749-754(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SCGB1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the Central region of human SCGB1D2.
NCBI Gene ID #:
10647
NCBI Official Name:
Secretoglobin family 1D member 2
NCBI Official Symbol:
SCGB1D2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
10 kDa
Protein Accession #:
O95969
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
O95969
User NOte:
Optimal dilutions for each application to be determined by the researcher.