MET Antibody

ProSci
Product Code: PSI-56-218
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-218-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

Further Information

Additional Names:
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met, MET
Application Note:
For WB starting dilution is: 1:1000
Background:
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Song, J., et al. Arch. Pathol. Lab. Med. 134(11):1702-1705(2010)
  • Thanseem, I., et al. Neurosci. Res. 68(2):137-141(2010)
  • Holgren, C., et al. Oncogene 29(38):5241-5253(2010)
  • Sugiura, T., et al. Clin. Immunol. 136(3):387-399(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ZNF593 antibody is generated from rabbits immunized with a His fusion protein from human MET.
NCBI Gene ID #:
4233
NCBI Official Name:
Hepatocyte growth factor receptor
NCBI Official Symbol:
MET
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
156 kDa
Protein Accession #:
P08581
Protein GI Number:
251757497
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P08581
User NOte:
Optimal dilutions for each application to be determined by the researcher.