LCP1 Antibody
| Code | Size | Price |
|---|
| PSI-60-157-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Plastin-2, L-plastin, LC64P, Lymphocyte cytosolic protein 1, LCP-1, LCP1, PLS2
Application Note:
For WB starting dilution is: 1:1000
Background:
Plastins are a family of actin-binding proteins that are
conserved throughout eukaryote evolution and expressed in most
tissues of higher eukaryotes. In humans, two ubiquitous plastin
isoforms (L and T) have been identified. Plastin 1 (otherwise known
as Fimbrin) is a third distinct plastin isoform which is
specifically expressed at high levels in the small intestine. The L
isoform is expressed only in hemopoietic cell lineages, while the T
isoform has been found in all other normal cells of solid tissues
that have replicative potential (fibroblasts, endothelial cells,
epithelial cells, melanocytes, etc.). However, L-plastin has been
found in many types of malignant human cells of non-hemopoietic
origin suggesting that its expression is induced accompanying
tumorigenesis in solid tissues.
Background References:
- Wabnitz, G.H., et al. Eur. J. Immunol. 40(9):2437-2449(2010)
- Janji, B., et al. J. Cell. Mol. Med. 14 (6A), 1264-1275 (2010) :
- Le Goff, E., et al. Cytoskeleton (Hoboken) 67(5):286-296(2010)
- Al Tanoury, Z., et al. PLoS ONE(2), E9210 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This LCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-335 amino acids from the Central region of human LCP1.
NCBI Gene ID #:
3936
NCBI Official Name:
Plastin-2
NCBI Official Symbol:
LCP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
P13796
Protein GI Number:
308153685
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P13796
User NOte:
Optimal dilutions for each application to be determined by the researcher.