COL6A2 Antibody
Code | Size | Price |
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PSI-58-453-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Collagen alpha-2(VI) chain, COL6A2
Application Note:
For WB starting dilution is: 1:1000
Background:
COL6A2 is one of the three alpha chains of type VI
collagen, a beaded filament collagen found in most connective
tissues. The product of this gene contains several domains similar
to von Willebrand Factor type A domains. These domains have been
shown to bind extracellular matrix proteins, an interaction that
explains the importance of this collagen in organizing matrix
components. Mutations in this gene are associated with Bethlem
myopathy and Ullrich scleroatonic muscular dystrophy. Three
transcript variants have been identified for this gene. [provided
by RefSeq].
Background References:
- Zhang, R.Z., et al. J. Biol. Chem. 285(13):10005-10015(2010)
- Bovolenta, M., et al. BMC Med. Genet. 11, 44 (2010) :
- Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
- Freise, C., et al. Matrix Biol. 28(8):480-489(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This COL6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of human COL6A2.
NCBI Gene ID #:
1292
NCBI Official Name:
Collagen alpha-2(VI) chain
NCBI Official Symbol:
COL6A2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
109 kDa
Protein Accession #:
P12110
Protein GI Number:
125987812
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P12110
User NOte:
Optimal dilutions for each application to be determined by the researcher.