RARB Antibody
| Code | Size | Price |
|---|
| PSI-59-680-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Retinoic acid receptor beta, RAR-beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon, RARB, HAP, NR1B2
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
This gene encodes retinoic acid receptor beta, a member of
the thyroid-steroid hormone receptor superfamily of nuclear
transcriptional regulators. This receptor localizes to the
cytoplasm and to subnuclear compartments. It binds retinoic acid,
the biologically active form of vitamin A which mediates cellular
signalling in embryonic morphogenesis, cell growth and
differentiation. It is thought that this protein limits growth of
many cell types by regulating gene expression. The gene was first
identified in a hepatocellular carcinoma where it flanks a
hepatitis B virus integration site. The gene expresses at least two
transcript variants; one additional transcript has been described,
but its full length nature has not been determined. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Miladi-Abdennadher, I., et al. Tumour Biol. 31(5):503-511(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This RARB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-195 amino acids from the Central region of human RARB.
NCBI Gene ID #:
5915
NCBI Official Name:
Retinoic acid receptor beta
NCBI Official Symbol:
RARB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
P10826
Protein GI Number:
17380507
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P10826
User NOte:
Optimal dilutions for each application to be determined by the researcher.