STS Antibody

ProSci
Product Code: PSI-57-790
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-790-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).
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STS Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in Hela cell line lysates (35ug/lane).
STS Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Steryl-sulfatase, Arylsulfatase C, ASC, Steroid sulfatase, Steryl-sulfate sulfohydrolase, STS, ARSC1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).
Background References:
  • Chanplakorn, N., et al. Breast Cancer Res. Treat. 120(3):639-648(2010)
  • Gruber, R., et al. J. Dermatol. Sci. 58(1):72-75(2010)
  • Canueto, J., et al.Eur Acad Dermatol Venereol (2010) In press :
  • Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This STS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 488-517 amino acids from the C-terminal region of human STS.
NCBI Gene ID #:
412
NCBI Official Name:
Steryl-sulfatase
NCBI Official Symbol:
STS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
P08842
Protein GI Number:
135006
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P08842
User NOte:
Optimal dilutions for each application to be determined by the researcher.