CASC3 Antibody

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ProSci
Product Code: PSI-62-776
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-62-776-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of CASC3 using rabbit polyclonal CASC3 Antibody (Mouse C-term) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CASC3 gene (Lane 2).
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Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of CASC3 using rabbit polyclonal CASC3 Antibody (Mouse C-term) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CASC3 gene (Lane 2).
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Documents

Further Information

Additional Names:
Protein CASC3, Cancer susceptibility candidate gene 3 protein homolog, Metastatic lymph node gene 51 protein homolog, MLN 51 homolog, Protein barentsz, Btz, mBtz, Casc3, Mln51
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Component of the dendritic ribonucleoprotein particles (RNPs) in hippocampal neurons. May play a role in mRNA transport.
Background References:
  • Macchi,P., J. Neurosci. 23 (13), 5778-5788 (2003)
  • Degot,S., Oncogene 21 (28), 4422-4434 (2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen:
This CASC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-233 amino acids from the C-terminal region of human CASC3.
NCBI Gene ID #:
192160
NCBI Official Name:
Protein CASC3
NCBI Official Symbol:
Casc3
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
Q8K3W3
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q8K3W3
User NOte:
Optimal dilutions for each application to be determined by the researcher.