VEGFD Antibody

ProSci
Product Code: PSI-62-227
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-227-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of anti-VEGF4 Antibody Pab (AP6292b) in 293 cell line lysates.
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VEGFD (VEGF4) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis of anti-VEGF4 Antibody Pab (AP6292b) in 293 cell line lysates.
VEGFD (VEGF4) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Vascular endothelial growth factor D, VEGF-D, c-Fos-induced growth factor, FIGF, FIGF, VEGFD
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
Background References:
  • Orlandini, M., et al., J. Biol. Chem. 278(45):44650-44656 (2003).
  • McColl, B.K., et al., J. Exp. Med. 198(6):863-868 (2003).
  • Rissanen, T.T., et al., Circ. Res. 92(10):1098-1106 (2003).
  • Nakamura, Y., et al., Clin. Cancer Res. 9(2):716-721 (2003).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This VEGFD (VEGF4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human VEGFD (VEGF4).
NCBI Gene ID #:
2277
NCBI Official Name:
Vascular endothelial growth factor D
NCBI Official Symbol:
FIGF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
O43915
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Signal Transduction
Swissprot #:
O43915
User NOte:
Optimal dilutions for each application to be determined by the researcher.