SGMS1 Antibody

ProSci
Product Code: PSI-57-124
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-124-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MCF-7 cell line lysates (35ug/lane).
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SGMS1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in MCF-7 cell line lysates (35ug/lane).
SGMS1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Phosphatidylcholine:ceramide cholinephosphotransferase 1, Medulla oblongata-derived protein, Protein Mob, Sphingomyelin synthase 1, Transmembrane protein 23, SGMS1, MOB, SMS1, TMEM23
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Lafont, E., et al. Cell Death Differ. 17(4):642-654(2010)
  • Vacaru, A.M., et al. J. Cell Biol. 185(6):1013-1027(2009)
  • Wang, W., et al. Plant Cell 20(11):3163-3179(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SGMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human SGMS1.
NCBI Gene ID #:
259230
NCBI Official Name:
Phosphatidylcholine:ceramide cholinephosphotransferase 1
NCBI Official Symbol:
SGMS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
Q86VZ5
Protein GI Number:
44888473
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q86VZ5
User NOte:
Optimal dilutions for each application to be determined by the researcher.