RAP1GDS1 Antibody

ProSci
Product Code: PSI-56-132
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-132-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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RAP1GDS1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).

RAP1GDS1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in HepG2,MDA-MB231 cell line lysates (35ug/lane).

Further Information

Additional Names:
Rap1 GTPase-GDP dissociation stimulator 1, Exchange factor smgGDS, SMG GDS protein, SMG P21 stimulatory GDP/GTP exchange protein, RAP1GDS1
Application Note:
For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000
Background:
The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).
Background References:
  • Schonherr, C., et al. Oncogene 29(19):2817-2830(2010)
  • Branham, M.T., et al. J. Biol. Chem. 284(37):24825-24839(2009)
  • Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009)
  • Tew, G.W., et al. J. Biol. Chem. 283(2):963-976(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RAP1GDS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the Central region of human RAP1GDS1.
NCBI Gene ID #:
5910
NCBI Official Name:
Rap1 GTPase-GDP dissociation stimulator 1
NCBI Official Symbol:
RAP1GDS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
P52306
Protein GI Number:
212276504
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P52306
User NOte:
Optimal dilutions for each application to be determined by the researcher.