SFRP2 Antibody
| Code | Size | Price |
|---|
| PSI-56-366-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1, SFRP2, FRP2, SARP1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the SFRP family that
contains a cysteine-rich domain homologous to the putative
Wnt-binding site of Frizzled proteins. SFRPs act as soluble
modulators of Wnt signaling. Methylation of this gene is a
potential marker for the presence of colorectal cancer. [provided
by RefSeq].
Background References:
- von Marschall, Z., et al. Biochem. Biophys. Res. Commun. 400(3):299-304(2010)
- Pehlivan, S., et al. Cancer Genet. Cytogenet. 201(2):128-132(2010)
- Kohno, H., et al. Oncol. Rep. 24(2):423-431(2010)
- Yamamura, S., et al. Mol. Cancer Ther. 9(6):1680-1687(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SFRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human SFRP2.
NCBI Gene ID #:
6423
NCBI Official Name:
Secreted frizzled-related protein 2
NCBI Official Symbol:
SFRP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q96HF1
Protein GI Number:
61216828
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q96HF1
User NOte:
Optimal dilutions for each application to be determined by the researcher.