MCF2 Antibody
| Code | Size | Price |
|---|
| PSI-56-509-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Proto-oncogene DBL, Proto-oncogene MCF-2, MCF2-transforming protein, DBL-transforming protein, MCF2, DBL
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The oncogenic protein encoded by this gene is a guanine
nucleotide exchange factor (GEF) that exerts control over some
members of the Rho family of small GTPases. Several transcript
variants encoding different isoforms have been found for this gene.
These isoforms exhibit different expression patterns and varying
levels of GEF activity.
Background References:
- Piton, A., et al. Mol. Psychiatry (2010) In press :
- Murakami, M., et al. Int. J. Cancer 123(3):500-510(2008)
- Murakami, M., et al. Cancer Biol. Ther. 7(5):677-688(2008)
- Rojas, R.J., et al. J. Biol. Chem. 282(40):29201-29210(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MCF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 804-833 amino acids from the C-terminal region of human MCF2.
NCBI Gene ID #:
4168
NCBI Official Name:
Proto-oncogene DBL
NCBI Official Symbol:
MCF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
108 kDa
Protein Accession #:
P10911
Protein GI Number:
92087039
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P10911
User NOte:
Optimal dilutions for each application to be determined by the researcher.