FZD2 Antibody

ProSci
Product Code: PSI-58-004
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-004-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Further Information

Additional Names:
Frizzled-2, Fz-2, hFz2, FzE2, FZD2
Application Note:
For WB starting dilution is: 1:1000
Background:
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung and in adult colon and ovary.
Background References:
  • Bazhin, A.V., et al. Cell. Mol. Life Sci. 67(5):817-828(2010)
  • Sato, A., et al. EMBO J. 29(1):41-54(2010)
  • Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
  • Ollila, H.M., et al. Mol. Psychiatry 14(4):351-353(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This FZD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 534-563 amino acids from the C-terminal region of human FZD2.
NCBI Gene ID #:
2535
NCBI Official Name:
Frizzled-2
NCBI Official Symbol:
FZD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
Q14332
Protein GI Number:
17433019
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction,Growth Factor
Swissprot #:
Q14332
User NOte:
Optimal dilutions for each application to be determined by the researcher.