REC8 Antibody
| Code | Size | Price |
|---|
| PSI-57-127-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Meiotic recombination protein REC8 homolog, Cohesin Rec8p, REC8, REC8L1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the kleisin family of SMC
(structural maintenance of chromosome) protein partners. The
protein localizes to the axial elements of chromosomes during
meiosis in both oocytes and spermatocytes. In the mouse, the
homologous protein is a key component of the meiotic cohesion
complex, which regulates sister chromatid cohesion and
recombination between homologous chromosomes. Multiple
alternatively spliced variants, encoding the same protein, have
been found for this gene.
Background References:
- Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)
- Erenpreisa, J., et al. Exp. Cell Res. 315(15):2593-2603(2009)
- Griffin, J., et al. Syst Biol Reprod Med 54(3):163-165(2008)
- Xu, H., et al. Dev. Cell 8(6):949-961(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This REC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 amino acids from the Central region of human REC8.
NCBI Gene ID #:
9985
NCBI Official Name:
Meiotic recombination protein REC8 homolog
NCBI Official Symbol:
REC8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
O95072
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
O95072
User NOte:
Optimal dilutions for each application to be determined by the researcher.