A2M Antibody
| Code | Size | Price |
|---|
| PSI-57-992-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-2-macroglobulin, Alpha-2-M, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, A2M, CPAMD5
Application Note:
For WB starting dilution is: 1:1000
Background:
Alpha-2-macroglobulin is a protease inhibitor and cytokine
transporter. It inhibits many proteases, including trypsin,
thrombin and collagenase. A2M is implicated in Alzheimer disease
(AD) due to its ability to mediate the clearance and degradation of
A-beta, the major component of beta-amyloid deposits. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Bruno, E., et al. Neurosci. Lett. 482(2):112-116(2010)
- Nalpas, B., et al. Gut 59(8):1120-1126(2010)
- Song, H., et al. Neurosci. Lett. 479(2):143-145(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This A2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1162-1192 amino acids from the C-terminal region of human A2M.
NCBI Gene ID #:
2
NCBI Official Name:
Alpha-2-macroglobulin
NCBI Official Symbol:
A2M
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
163 kDa
Protein Accession #:
P01023
Protein GI Number:
308153640
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P01023
User NOte:
Optimal dilutions for each application to be determined by the researcher.