PCSK5 Antibody
| Code | Size | Price |
|---|
| PSI-60-811-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Proprotein convertase subtilisin/kexin type 5, 3421-, Proprotein convertase 5, PC5, Proprotein convertase 6, PC6, hPC6, Subtilisin/kexin-like protease PC5, PCSK5, PC5, PC6
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the
subtilisin-like proprotein convertase family. The members of this
family are proprotein convertases that process latent precursor
proteins into their biologically active products. This encoded
protein mediates posttranslational endoproteolytic processing for
several integrin alpha subunits. It is thought to process prorenin,
pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein
gp160. Multiple transcript variants encoding different isoforms
have been found for this gene.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Heng, S., et al. Endocrinology 151(8):3909-3917(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PCSK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the N-terminal region of human PCSK5.
NCBI Gene ID #:
5125
NCBI Official Name:
Proprotein convertase subtilisin/kexin type 5
NCBI Official Symbol:
PCSK5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
207 kDa
Protein Accession #:
Q92824
Protein GI Number:
357529585
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q92824
User NOte:
Optimal dilutions for each application to be determined by the researcher.