TBX3 Antibody
Code | Size | Price |
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PSI-58-144-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
T-box transcription factor TBX3, T-box protein 3, TBX3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of a phylogenetically conserved
family of genes that share a common DNA-binding domain, the T-box.
T-box genes encode transcription factors involved in the regulation
of developmental processes. This protein is a transcriptional
repressor and is thought to play a role in the anterior/posterior
axis of the tetrapod forelimb. Mutations in this gene cause
ulnar-mammary syndrome, affecting limb, apocrine gland, tooth,
hair, and genital development. Alternative splicing of this gene
results in three transcript variants encoding different isoforms;
however, the full length nature of one variant has not been
determined.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)
- Christoffels, V.M., et al. Circ. Res. 106(2):240-254(2010)
- Pfeufer, A., et al. Nat. Genet. 42(2):153-159(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TBX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human TBX3.
NCBI Gene ID #:
6926
NCBI Official Name:
T-box transcription factor TBX3
NCBI Official Symbol:
TBX3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
O15119
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
O15119
User NOte:
Optimal dilutions for each application to be determined by the researcher.