PCSK6 Antibody
| Code | Size | Price |
|---|
| PSI-58-025-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Proprotein convertase subtilisin/kexin type 6, 3421-, Paired basic amino acid cleaving enzyme 4, Subtilisin-like proprotein convertase 4, SPC4, Subtilisin/kexin-like protease PACE4, PCSK6, PACE4
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the
subtilisin-like proprotein convertase family. The members of this
family are proprotein convertases that process latent precursor
proteins into their biologically active products. This encoded
protein is a calcium-dependent serine endoprotease that can cleave
precursor protein at their paired basic amino acid processing
sites. Some of its substrates are - transforming growth factor beta
related proteins, proalbumin, and von Willebrand factor. This gene
is thought to play a role in tumor progression. Alternatively
spliced transcript variants encoding different isoforms have been
identified.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Fuller, J.A., et al. Invest. Ophthalmol. Vis. Sci. 50(12):5759-5768(2009)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PCSK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-688 amino acids from the C-terminal region of human PCSK6.
NCBI Gene ID #:
5046
NCBI Official Name:
Proprotein convertase subtilisin/kexin type 6
NCBI Official Symbol:
PCSK6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
106 kDa
Protein Accession #:
P29122
Protein GI Number:
129542
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P29122
User NOte:
Optimal dilutions for each application to be determined by the researcher.