CELA1 Antibody
| Code | Size | Price |
|---|
| PSI-59-436-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Chymotrypsin-like elastase family member 1, Elastase-1, Pancreatic elastase 1, CELA1, ELA1
Application Note:
For WB starting dilution is: 1:1000
Background:
Elastases form a subfamily of serine proteases that
hydrolyze many proteins in addition to elastin. Humans have six
elastase genes which encode the structurally similar proteins
elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases,
pancreatic elastase 1 is not expressed in the pancreas. To date,
elastase 1 expression has only been detected in skin keratinocytes.
Clinical literature that describes human elastase 1 activity in the
pancreas or fecal material is actually referring to
chymotrypsin-like elastase family, member 3B.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CELA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CELA1.
NCBI Gene ID #:
1990
NCBI Official Name:
Chymotrypsin-like elastase family member 1
NCBI Official Symbol:
CELA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
Q9UNI1
Protein GI Number:
62298049
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9UNI1
User NOte:
Optimal dilutions for each application to be determined by the researcher.