USP1 Antibody
| Code | Size | Price |
|---|
| PSI-58-780-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the ubiquitin-specific
processing (UBP) family of proteases that is a deubiquitinating
enzyme (DUB) with His and Cys domains. This protein is located in
the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused
precursors and ubiquitinylated proteins. The protein specifically
deubiquitinates a protein in the Fanconi anemia (FA) DNA repair
pathway. Alternate transcriptional splice variants have been
characterized.
Background References:
- Barroso, E., et al. Breast Cancer Res. Treat. 118(3):655-660(2009)
- McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18(9):2549-2552(2009)
- Cohn, M.A., et al. J. Biol. Chem. 284(8):5343-5351(2009)
- Cohn, M.A., et al. Mol. Cell 28(5):786-797(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This USP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 662-690 amino acids from the C-terminal region of human USP1.
NCBI Gene ID #:
7398
NCBI Official Name:
Ubiquitin carboxyl-terminal hydrolase 1
NCBI Official Symbol:
USP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
O94782
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
O94782
User NOte:
Optimal dilutions for each application to be determined by the researcher.