MARCH4 Antibody
| Code | Size | Price |
|---|
| PSI-56-995-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase MARCH4, 632-, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, MARCH-IV, RING finger protein 174, MARCH4, KIAA1399, RNF174
Application Note:
For WB starting dilution is: 1:1000
Background:
MARCH4 is a member of the MARCH family of membrane-bound
E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin
(see MIM 191339) to target lysines in substrate proteins, thereby
signaling their vesicular transport between membrane compartments.
MARCH4 reduces surface accumulation of several membrane
glycoproteins by directing them to the endosomal compartment
(Bartee et al., 2004 [PubMed 14722266]).
Background References:
- Bartee, E., et al. J. Virol. 78(3):1109-1120(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MARCH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 amino acids from the C-terminal region of human MARCH4.
NCBI Gene ID #:
57574
NCBI Official Name:
E3 ubiquitin-protein ligase MARCH4
NCBI Official Symbol:
Mar-04
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q9P2E8
Protein GI Number:
59798475
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9P2E8
User NOte:
Optimal dilutions for each application to be determined by the researcher.