PRSS8 Antibody

ProSci
Product Code: PSI-57-560
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-560-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Prostasin, 3421-, Channel-activating protease 1, CAP1, Serine protease 8, Prostasin light chain, Prostasin heavy chain, PRSS8
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.
Background References:
  • Chen, Y.W., et al. J. Biol. Chem. 285(41):31755-31762(2010)
  • Chen, M., et al. Mol. Cell. Biochem. 337 (1-2), 259-266 (2010) :
  • Fu, Y.Y., et al. Hum. Reprod. 25(3):623-632(2010)
  • Ko, T., et al. J. Biomed. Biotechnol. 2010, 793843 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PRSS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human PRSS8.
NCBI Gene ID #:
5652
NCBI Official Name:
Prostasin
NCBI Official Symbol:
PRSS8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
Q16651
Protein GI Number:
2833277
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q16651
User NOte:
Optimal dilutions for each application to be determined by the researcher.