RNF40 Antibody
| Code | Size | Price |
|---|
| PSI-57-676-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase BRE1B, BRE1-B, 632-, 95 kDa retinoblastoma-associated protein, RBP95, RING finger protein 40, RNF40, BRE1B, KIAA0661
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene contains a RING finger, a
motif known to be involved in protein-protein and protein-DNA
interactions. This protein was reported to interact with the tumor
suppressor protein RB1. Studies of the rat counterpart suggested
that this protein may function as an E3 ubiquitin-protein ligase,
and facilitate the ubiquitination and degradation of syntaxin 1,
which is an essential component of the neurotransmitter release
machinery.
Background References:
- Chernikova, S.B., et al. Radiat. Res. 174(5):558-565(2010)
- Kim, J., et al. Cell 137(3):459-471(2009)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This RNF40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 697-725 amino acids from the C-terminal region of human RNF40.
NCBI Gene ID #:
9810
NCBI Official Name:
E3 ubiquitin-protein ligase BRE1B
NCBI Official Symbol:
RNF40
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
114 kDa
Protein Accession #:
O75150
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
O75150
User NOte:
Optimal dilutions for each application to be determined by the researcher.