ZNRF1 Antibody
| Code | Size | Price |
|---|
| PSI-58-699-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase ZNRF1, 632-, Nerve injury-induced gene 283 protein, Zinc/RING finger protein 1, ZNRF1, NIN283
Application Note:
For WB starting dilution is: 1:1000
Background:
In a study identifying genes in rat that are upregulated
in response to nerve damage, a gene which is highly expressed in
ganglia and in the central nervous system was found. The protein
encoded by the rat gene contains both a zinc finger and a RING
finger motif and is localized in the endosome/lysosome compartment,
indicating that it may be involved in ubiquitin-mediated protein
modification. The protein encoded by this human gene is highly
similar in sequence to that encoded by the rat gene. [provided by
RefSeq].
Background References:
- Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
- Yoshida, K., et al. Biochem. Biophys. Res. Commun. 389(3):506-511(2009)
- Markson, G., et al. Genome Res. 19(10):1905-1911(2009)
- van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ZNRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the Central region of human ZNRF1.
NCBI Gene ID #:
84937
NCBI Official Name:
E3 ubiquitin-protein ligase ZNRF1
NCBI Official Symbol:
ZNRF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
Q8ND25
Protein GI Number:
126253846
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8ND25
User NOte:
Optimal dilutions for each application to be determined by the researcher.