USP14 Antibody
| Code | Size | Price |
|---|
| PSI-60-770-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14, USP14, TGT
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the ubiquitin-specific
processing (UBP) family of proteases that is a deubiquitinating
enzyme (DUB) with His and Cys domains. This protein is located in
the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused
precursors and ubiquitinylated proteins. Mice with a mutation that
results in reduced expression of the ortholog of this protein are
retarded for growth, develop severe tremors by 2 to 3 weeks of age
followed by hindlimb paralysis and death by 6 to 10 weeks of age.
Alternate transcriptional splice variants, encoding different
isoforms, have been characterized.
Background References:
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Chen, P.C., et al. J. Neurosci. 29(35):10909-10919(2009)
- Mines, M.A., et al. J. Biol. Chem. 284(9):5742-5752(2009)
- Nagai, A., et al. Biochem. Biophys. Res. Commun. 379(4):995-1000(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Bovine
Immunogen:
This USP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-383 amino acids from the C-terminal region of human USP14.
NCBI Gene ID #:
9097
NCBI Official Name:
Ubiquitin carboxyl-terminal hydrolase 14
NCBI Official Symbol:
USP14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
P54578
Protein GI Number:
1729927
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P54578
User NOte:
Optimal dilutions for each application to be determined by the researcher.