USP16 Antibody
| Code | Size | Price |
|---|
| PSI-58-690-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255|HAMAP-Rule:MF_03062}, 341912 {ECO:0000255|HAMAP-Rule:MF_03062}, Deubiquitinating enzyme 16 {ECO:0000255|HAMAP-Rule:MF_03062}, Ubiquitin thioesterase 16 {ECO:0000255|HAMAP-Rule:MF_03062}, Ubiquitin-processing protease UBP-M, Ubiquitin-specific-processing protease 16 {ECO:0000255|HAMAP-Rule:MF_03062}, USP16 {ECO:0000255|HAMAP-Rule:MF_03062}
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a deubiquitinating enzyme that is
phosphorylated at the onset of mitosis and then dephosphorylated at
the metaphase/anaphase transition. It can deubiquitinate H2A, one
of two major ubiquitinated proteins of chromatin, in vitro and a
mutant form of the protein was shown to block cell division.
Alternate transcriptional splice variants, encoding different
isoforms, have been characterized.
Background References:
- Gelsi-Boyer, V., et al. BMC Cancer 8, 299 (2008) :
- Joo, H.Y., et al. Nature 449(7165):1068-1072(2007)
- Pai, M.T., et al. J. Mol. Biol. 370(2):290-302(2007)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This USP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the N-terminal region of human USP16.
NCBI Gene ID #:
10600
NCBI Official Name:
Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255|HAMAP-Rule:MF_03062}
NCBI Official Symbol:
USP16
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
94 kDa
Protein Accession #:
Q9Y5T5
Protein GI Number:
6686071
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9Y5T5
User NOte:
Optimal dilutions for each application to be determined by the researcher.