RCBTB1 Antibody
| Code | Size | Price |
|---|
| PSI-58-739-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1, RCBTB1, CLLD7, E45
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein with an N-terminal RCC1 domain
and a C-terminal BTB (broad complex, tramtrack and bric-a-brac)
domain. In rat, over-expression of this gene in vascular smooth
muscle cells induced cellular hypertrophy. In rat, the C-terminus
of RCBTB1 interacts with the angiotensin II receptor-1A. In humans,
this gene maps to a region of chromosome 13q that is frequently
deleted in B-cell chronic lymphocytic leukemia and other lymphoid
malignancies.
Background References:
- Genuneit, J., et al. Clin. Exp. Allergy 39(12):1875-1888(2009)
- Guo, D.F., et al. J. Biol. Chem. 279(20):21109-21120(2004)
- Dunham, A., et al. Nature 428(6982):522-528(2004)
- Solomou, E.E., et al. Leuk. Lymphoma 44(9):1579-1585(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RCBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-377 amino acids from the Central region of human RCBTB1.
NCBI Gene ID #:
55213
NCBI Official Name:
RCC1 and BTB domain-containing protein 1
NCBI Official Symbol:
RCBTB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q8NDN9
Protein GI Number:
74751227
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8NDN9
User NOte:
Optimal dilutions for each application to be determined by the researcher.