UBA6 Antibody

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ProSci
Product Code: PSI-58-782
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-782-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis in K562 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Ubiquitin-like modifier-activating enzyme 6, Ubiquitin-activating enzyme 6, Monocyte protein 4, MOP-4, Ubiquitin-activating enzyme E1-like protein 2, E1-L2, UBA6, MOP4, UBE1L2
Application Note:
For WB starting dilution is: 1:1000
Background:
Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).
Background References:
  • Groettrup, M., et al. Trends Biochem. Sci. 33(5):230-237(2008)
  • Chiu, Y.H., et al. Mol. Cell 27(6):1014-1023(2007)
  • Pelzer, C., et al. J. Biol. Chem. 282(32):23010-23014(2007)
  • Jin, J., et al. Nature 447(7148):1135-1138(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This UBA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-889 amino acids from the C-terminal region of human UBA6.
NCBI Gene ID #:
55236
NCBI Official Name:
Ubiquitin-like modifier-activating enzyme 6
NCBI Official Symbol:
UBA6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
118 kDa
Protein Accession #:
A0AVT1
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
A0AVT1
User NOte:
Optimal dilutions for each application to be determined by the researcher.