L3MBTL2 Antibody
| Code | Size | Price |
|---|
| PSI-57-579-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Lethal(3)malignant brain tumor-like protein 2, H-l(3)mbt-like protein 2, L(3)mbt-like protein 2, L3MBTL2
Application Note:
For WB starting dilution is: 1:1000
Background:
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Background References:
- Guo, Y., et al. Nucleic Acids Res. 37(7):2204-2210(2009)
- Lechtenberg, B.C., et al. Protein Sci. 18(3):657-661(2009)
- Trojer, P., et al. Cell 129(5):915-928(2007)
- Collins, J.E., et al. Genome Biol.(10), R84 (2004) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This L3MBTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 627-656 amino acids from the C-terminal region of human L3MBTL2.
NCBI Gene ID #:
83746
NCBI Official Name:
Lethal(3)malignant brain tumor-like protein 2
NCBI Official Symbol:
L3MBTL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q969R5
Protein GI Number:
27734418
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q969R5
User NOte:
Optimal dilutions for each application to be determined by the researcher.